Monday, January 14, 2008
A Possible Mechanism for C-Peptide
There is a new study published in today's issue of Chemical & Engineering News that gives a possible mechanism for activation of the C-peptide. The authors suggest that a metal ion may change the conformation of C-peptide, which may, in turn, allow glucose to enter red blood cells through a glucose transporter (GLUT1). While type 2 diabetics may have normal to elevated levels of C-peptide (which has led some to believe that it may contribute to complications), other studies have shown beneficial effects of the peptide (as described by this study). People with type 1 diabetes generally produce little to no C-peptide. I originally saw this story on Science Daily News.